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10.1016/j.freeradbiomed.2022.10.004 214 ZhangS.ZhangL.LuH.YaoY.LiuX.HouJ

Nat Commun 10(1):2978, 2019

Results with NAC for chronic lung disease are mixed

Concurrently, ACC inhibition reduces inflammatory macrophage recruitment through blockade of chemokine receptors CCR2/CCR5 (e.g., via cenicriviroc), thereby attenuating pro-inflammatory cytokine production in pulmonary niches (Tacke and Weiskirchen, 2018)