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optionally substituted polyether, aryl having 6 to 10 ring atoms, C3-C8 cycloalkyl, heterocycloalkyl having 3 to 10 ring atoms, heteroaryl having 5 to 10 ring atoms, and any combination thereof, said alkyl and alkenyl being optionally interrupted by one or more heteroatom or chemical groups selected from -O-, -S-, -C(O)-, -NR-, -C(O)NR-, -NR-C(O)-, -NR- C(O)-NR-, -NR-C(O)-O-, -O-C(O)NR- and triazole, R and R being independently selected from H and C1 -C6 alkyl, and pharmaceutically acceptable salts thereof

10.1097/OPX.0b013e318194e767 141 PludowskiP.HolickM