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doi: 10.1016/j.neuroscience.2022.05.030 6 LvZFanHGaoMZhangXLiGFanYet al

(2) severe G6PD deficiency is much more common in males than in females

Discussion Surfing the literature, the answer to the initial question whether there is evidence of liver toxicity by opioids, synthetic opioids and mainly by fentanyl is positive