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A.KamiyaT.BurrittD

10.1016/S2213-8587(13)70084-6 330

Aberrant glycosylation has been observed to affect a number of oncogenes during tumorigenesis, including EGFR, where increased glycan branching results in increased residency time at the plasma membrane, thus increasing its active period (Lajoie et al, 2007)

It is not possible with the available data to determine precisely how many of the 1,731 class 1 genes identified in this study are directly regulated by SLIM1 via promoter binding in vivo