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Based on these data, monthly dosing may be achievable with MK3655

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ME2 is highly sensitive to MDSA and EA inhibition, whereas ME1 is notably less sensitive, indicating that both inhibitors bind to allosteric sites

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doi: 10.1093/bioinformatics/btv351 95 SimpsonJ

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(2006) A New Paradigm: Manganese Superoxide Dismutase Influences the Production of H 2 O 2 in Cells and Thereby Their Biological State

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