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In summary, the evolution of Parkinson's disease treatment can be summarized as follows: a shift from purely symptomatic control to multi-targeted synergistic effects, and from a predominantly drug-based management model to a multi-modal intervention approach (Fig

This distinction matters because it means existing contamination still poses a risk

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Moreover, imbalanced Mn levels may contribute to the pathogenesis of other neurological disorders, such as Huntingtons disease (HD), attention-deficit/hyperactivity disorder (ADHD), and Alzheimers disease (AD)