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The DAC-modified version binds covalently to albumin in the bloodstream, extending its reported terminal half-life to approximately 68 days, compared with minutes for unmodified GHRH analogues

However, this weakening action appeared less pronounced when Ipamorelin was introduced alongside ghrelin, pointing to the possibility that Ipamorelin may not only support gastric muscle contractility but may also offset negative actions caused by certain interventions