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renal impairment can further exacerbate neuropathic symptoms through the accumulation of uremic toxins that adversely affect nerve function

doi: 10.3389/fmicb.2026.1771106 Received 18 December 2025 Revised 14 January 2026 Accepted 19 January 2026 Published 18 February 2026 Volume 17 - 2026 Edited by Valrio Monteiro-Neto, Federal University of Maranho, Brazil Reviewed by Emmanuel Adase, Centre for Plant Medicine Research (CPMR), Ghana Remziye Yilmaz, Hacettepe University, Trkiye Updates Copyright 2026 Tenea, Marinas, Gradisteanu Pircalabioru, Hidalgo, Chifiriuc and Noboa

A previous study has also demonstrated that systemic administration of KA induces contraction and even death of piriform cortical neurons

Effects of external counter-pressure in the treatment of hemorrhagic shock