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Well, even though our bodies are designed to fight free radicals with the help of powerful antioxidants such as glutathione, some factors like aging, stress, alcohol consumption, smoking, pollution, and a poor diet can lead to excess free radical production

However, oxidative stress is probably better understood as a disruption of the interplay between different inter-related cellular redox systems and their control (Jones, 2006)

Emerging evidence has demonstrated that CD44 can serve as a stimulator or promoter for EMT process through regulating related pathways [6]

Key molecules such as proliferative enhancers, cytokines, transcription factors, growth factors, apoptosis inhibitors, and growth factor receptors play crucial roles in cancer development (349, 350)