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Although hormetic mechanisms have been identified in the brain especially with regard to Nrf2 activation in astrocytes (Schmidlin et al., 2019

[PubMed: 9734366] 34

Situational Skin Spots Ageing or post-pregnancy period can shoot up uneven and uncontrolled production of melanin, which leads to pigmentation

The repeated social defeat stress increased the inflammatory signaling pathways, which led to prolonged anxiety and social deficits (Lee et al., 2020)