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A study further revealed that the exonuclease MYG1 promotes tumor adaptation and progression in CRC by coordinating nuclearmitochondrial signaling, thereby boosting both glycolysis and mitochondrial function [68]

Many patients use GLP-1 injections for a set period before transitioning to maintenance support

Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density

For instance, co-administration of curcumin with 5-FU or cisplatin has been shown to significantly improve the cytotoxic effects of these drugs on GC cells, leading to increased cell death and reduced tumor growth compared to chemotherapy alone