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The near-infrared II (NIR-II) area photothermal therapy (PTT) performance of HAuNS@PEG-bio is demonstrated to be effective, and the elevation of temperature at the tumor site stimulates blood circulation to mitigate the hypoxia within the tumor microenvironment (TME) (159)

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HDAC3 and HDAC11, for instance, regulate oxidative stress responses and A metabolism, whereas HDAC7 contributes to tau pathology by suppressing lysosomal biogenesis through transcription factor EB (TFEB) deacetylation and by enhancing inflammatory signaling via the IKKNF-B pathway 31