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Without them, essential processes like digestion, DNA replication, and muscle or nerve function would be too slow to sustain life

Traynelis, S.F., Wollmuth, L.P., McBain, C.J., Menniti, F.S., Vance, K.M., Ogden, K.K., Hansen, K.B., Yuan, H., Myers, S.J., and Dingledine, R., Pharmacol

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T N primarily have slow glycolysis and mainly rely on oxidative phosphorylation (OXPHOS) and fatty acid oxidation, but undergo a metabolic shift from OXPHOS to aerobic glycolysis as they become T EFF [107,108,109,110]