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10.1016/j.tim.2022.07.001 22

found that metformin inhibits the palmitic acid (PA)-induced upregulation of periostin (POSTN), which in turn increases p53 expression in VSMCs

The anti-atherogenic mechanism of myriocin may be linked to promote cholesterol efflux via this pathway 129

Therefore, it is advised to discuss the use of NAC with your healthcare provider if you are taking any medications to ensure safety and appropriateness