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Additionally, miRNA subtype miR-205 is a target for oxidative stress and autophagy treatment in AKI (Fig

Astrocyte-derived lactate is proposed to be transferred to neurons through MCTs, where it is primarily used, after conversion to pyruvate, as a rapid energy substrate, known as the ANLS hypothesis 50

Cang W, Wu A, Gu L, et al

The aim of this strategy is to reduce the bacterial burden (as in this phase it is virtually impossible to eradicate the pathogen) and, thus, reduce the inflammatory response that leads to structural lung damage and loss of function,4,78 avoiding the cumbersome and toxic iatrogenic effects associated to oral or intravenous route.79 It seems that this strategy may reduce the frequency and severity of respiratory exacerbations and the decline in lung function.80,81 One trial conducted in 2000 randomly assigned 74 patients with non-CF BE and P