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One of the RCTs found significant mean improvements in Clinical Global Impressions-Improvement (CGI-I) score and cellular methylation capacity, but not in the Aberrant Behaviour Checklist (ABC), Social Responsiveness Scale (SRS) or GSH metabolism, with those who had the lowest methionine status at baseline (suggesting impaired methylation capacity) significantly more likely to respond to supplementation

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(+)-Abscisic acid metabolism, 3-ketoacyl-coenzyme a synthase gene expression, and very-long-chain monounsaturated fatty acid biosynthesis in brassica napus embryos