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For inherited B12 deficiency, treatment is guided by the genetic condition

AOD-9604 was advanced through Phase I and Phase II clinical trials by Metabolic Pharmaceuticals between roughly 2003 and 2007 enrolling approximately 900 participants in total

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When deficiency is suspected based on clinical features (fatigue, paraesthesia, cognitive changes) or risk factors (vegan diet, gastric surgery, certain medications), serum B12 measurement guides appropriate intervention