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A promising implication is that interventions that increase GSH levels early in FEP may have the potential to alter the prognostic trajectory of psychosis (See SupplementaryTranslational Relevance for further details)

Step 1: aldol cleavage and intermediate formation In the first step, the -amino group of a lysine residue (Lys 132 ) in the active site performs a nucleophilic attack on the carbonyl carbon (C-2) of sedoheptulose 7-phosphate