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[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations

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Consistently, average adipocyte area doubled in WT mice while it increased only 1.5-fold with age in Has1,3 dko mice and was less than WT mice

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