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Abstract Idiopathic male infertility (IMI) refers to the condition where semen quality declines, but exact causatives are not identified

Retinal fluorescein and indocyanine green angiography is helpful to study the macula and screen for associated vasculitis, detect ischemic areas and preretinal, prepapillary or choroidal neovascular complications, and it may provide information about the etiology and be needed to assess the therapeutic response

Meanwhile, Cereblon-based degraders such as RP03707 have also been developed to target oncogenic KRAS G12C, further demonstrating the versatility and potential of PROTAC technology in the KRAS-targeted drug discovery