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Therefore, the combined metabolic and functional disruptions in DAAs and reactive astrocytes exacerbate neuronal dysfunction, cellular pathophysiology, and cell death, contributing to progression in CNS pathology

Based on studies involving gene-targeted mice and cell culture experiments, the significance of AMP-activated protein kinase (AMPK), p21-activated kinase 2 (PAK2), cGMP-dependent protein kinase type I (cGKI), Janus kinase 3 (JAK3), mitogen and stress-activated protein kinase (MSK1/2), and phosphoinositide-dependent kinase 1 (PDK1) for eryptosis has been studied

In the early development of HT, the diversity of gut microbiota did not change significantly, but the flora structure had quietly changed