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Hindmarsh PC, Matthews DR, Brain CE, Pringle PJ, di Silvio L, Kurtz AB, et al

doi: 10.1002/cphy.c130036, 30

A recent metallomic study has found significantly lower cortical lithium (Li) in mild cognitive impairment and AD with selective sequestration of Li within amyloid plaques, implying an early disturbance of endogenous Li homeostasis in vulnerable cortex while serum levels remain unchanged

However, rat studies with SARMs suggest that several compounds may hold significant BMD-increasing potential: Ostarine can have a positive effect on early bone healing and leads to the improvement of several microstructural bone indices in rat osteoporosis models [18, 19]