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486(7402):207214 Wang HM et al (2019) Inhibition of LPS-induced oxidative damages and potential anti-inflammatory effects of phyllanthus emblica extract via down-regulating NF-B, COX-2, and iNOS in RAW 264.7 cells

As of early 2026, the TRIUMPH program is fully enrolled across most arms, with topline readouts expected on a staggered timeline

The culture was split into two 300 ml cultures and each flask was diluted to 1.0 10 6 cells/mL, usually leading to a final volume of 600 mL that complies with the ratio of air to cell medium of 4:1

Specific alterations include reductions in Prevotella , Coprococcus , and Veillonellaceae , alongside overgrowth of Desulfovibrio (positively correlated with Autism spectrum disorder severity) (258), Sutterella , Ruminococcus , Clostridium , Megamonas , and Candida ( 259, 260), accompanied by an elevated Firmicutes/Bacteroidetes ratio (255)