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Disruption of the pbggcs gene resulted in attenuated development of oocysts and subsequent failure to produce sporozoites, as evidenced by the production of an oocyst capsule that is highly heterogeneous as to thickness, the loss of mitochondria membrane potential in the mutant oocysts, and abnormal patterns of expression of the circumsporozoite (CS) protein [23]

[2] Understanding these baseline requirements helps individuals and healthcare professionals assess whether dietary intake or supplementation may be necessary