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In an oncogenic context, the IGF family regulates a number of biological processes such as cancer cell proliferation, apoptosis, metabolism and protein synthesis, which are closely associated with the activation of PI3K/AKT signaling, which subsequently promotes the transcription of downstream pro-oncogenic target genes such as c-Myc and HIF-1 (77)

It may also provide potential gastrointestinal benefits by strengthening the stomach lining and reducing ulcers

Global burden for dengue and the evolving pattern in the past 30 years

(3), TME-derived plasma CXCL10 = (plasma CXCL10 of tumor-bearing ovariectomy mice) (tumor-derived plasma CXCL10) (plasma CXCL10 of control mice)