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patients in both arms received folic acid, vitamin B12, and dexamethasone [see Dosage and Administration (2.4)]

Because it stimulates the upstream signaling step (rather than supplying GH directly), sermorelin is commonly described as helping preserve the GH axiss built-in feedback controls including inhibitory tone from somatostatin and downstream regulation via IGF-1 which may reduce the likelihood of sustained, non-physiologic hormone elevations in research models

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