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Summary Klotho is an anti-aging agent that is expressed primarily in the kidneys and the cerebral choroid plexus, but also in many other different tissues and organs, such as the gonads and the pituitary gland

Another Gln transporter SLC1A5 inhibitor, V-9302, selectively blocked Gln uptake by TNBC cells, promoted the activation of CD4 + and CD8 + T cells, and reduced Treg levels in a TNBC mouse model (Table 1)