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What exactly causes vitiligo is difficult to pinpoint, although it is thought to be a combination of a number of factors, including: Autoimmune Reaction: Vitiligo is generally regarded as an autoimmune disease whereby the body begins to attack its own melanocytes (the cells responsible for producing melanin) and either destroys the cells or leaves them damaged and nonfunctional

FIGURE 2 7.2 CAT assays CAT is a heme-containing enzyme that catalyzes H 2 O 2 decomposition into water and O 2 , providing cellular protection against oxidative damage (Figure 2B)

Maximum binding was defined as the best-fit value for the top of each curve computed in Prism