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Studies have demonstrated that increased intestinal permeability owing to gut microbial dysbiosis results in the accumulation of bacterial metabolites, such as phenolic compounds derived from aromatic amino acids, in the skin, thereby affecting epidermal differentiation and compromising skin integrity (Mahmud et al., 2022)

Then, counts were converted into counts per million (cpm) and then log 2 transformed

The American Journal of Physiology, 262 (2 Pt 2), H313H317

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