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Description

435 Inhibiting lactate shuttle Lactate transport primarily relies on MCTs

administration of glucose, suggesting a link between LAC-related transport of acetyl groups and glucose signaling pathways, especially under conditions of metabolic stress [69]

In addition, network statistical matrices such as degree centrality, betweenness, or clustering coefficients facilitate prioritizing key genes for experimental validation, especially in the case of TNBC, where there are very few druggable targets (296)