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5 Progress in research on clinical intervention strategies Table 2 summarizes key intervention strategies and their mechanisms, helping to provide a clearer understanding of how each strategy targets ferroptosis and its potential application in cardiovascular diseases and other related conditions (12, 37)

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Whether a specific transporter exists for glutathione import into the ER requires further investigation, but it is clear that the selective transport of GSH would provide one possible mechanism for the regulation of the [GSH]:[GSSG] ratio in the ER lumen