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MT3 receptors may affect the expression of enzymes involved in detoxification and suppress proliferation [44, 45]

Acquired immunity was found to be mainly associated with a Th1 type IFN- and TNF pulmonary inflammatory and antibody response, IL-4, IL-5, and eosinophils are of negligible importance meanwhile, IL-10 and IgG4 negates protection and are associated with re-infection ( Utilizing advancements in technology, vaccine development has, in the recent past, shifted focus from irradiated parasite vaccines to specific antigen molecules