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doi: 10.1016/j.kint.2020.05.056 9 LiangJChenBLiYNieDLeiCBYangQet al

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Hepcidin, produced by the liver in response to high iron stores or inflammation, travels though the blood stream to the intestines where it reduces iron absorption

In the early stage of ALI, PAMPs such as LPS promote the polarization of lung macrophages into the M1 phenotype through the TLR4/NF-B signaling pathway (119)