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SARS-CoV immunization studies in animal models have thus produced results that vary greatly in terms of protective efficacy, immunopathology and potential ADE, depending on the vaccine strategy employed

The inert chemistry of the MSIA tips provide reduced nonspecific binding, lowering background and minimizing the work load on LC systems, which contribute to increased signal-to-noise and improved assay sensitivity, as shown in Figure 2

In macrophages with the M1-like phenotype, arginine is converted into nitric oxide (NO) and citrulline via inducible nitric oxide synthase (iNOS), and this anabolic pathway is closely associated with macrophage cytotoxicity and antitumor effects

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