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Raft associated interaction of CD44 with the cytoskeleton

This work underscores the therapeutic versatility of PROTAC prodrugs, demonstrating their potential not only for TPD but also for immunomodulatory intervention in cancer

Methods: Using a combination of human CCA cells and primary tumours, we analysed the levels and function of protein SUMOylation, identifying deregulated SUMOylated proteins by immunoprecipitation and mass spectrometry analysis