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These symptoms significantly impair quality of life and often emerge before the onset of motor deficits ( 5 Astaxanthin (AST) Carotenoids have long been recognized for their positive effects on individuals health, with some acting as precursors to vitamin A, essential for various biological functions, while others, known as non-provitamin A carotenoids, offer protective benefits such as defense against photodamage ( Astaxanthin is recognized as a dietary supplement and is readily accessible, with no significant adverse effects reported to date, making it both a safe and cost-effective option for further investigation ( Haematococcus pluvialis is predominantly the (3S,3S) form, whereas yeast-derived astaxanthin is rich in the (3R,3R) isomer, and synthetic astaxanthin typically contains all three in approximately a 1:2:1 ratio