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The underlying pathologic mechanisms of primary MS fatigue are poorly understood, with proposed theories including structural damage of white and gray matter, inflammatory processes including elevated cytokines, endocrine dysfunction, and maladaptive network recruitment attributable to distributed lesions or inflammation

These are available over the counter or may be prescribed in specific doses

This visualization further reinforces the conclusion that domain-specific embeddings, such as ClinicalBERT, outperform traditional feature extraction methods like OHE, particularly in tasks involving complex, real-world clinical data

International Journal of Cardiology