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Diagnosis of endocrine irAEs is often delayed due to the subtle nature of signs and symptoms that often overlap with symptoms typically experienced by patients with advanced cancer, including vomiting, headache, nausea and fatigue

Effects of muscarinic ACh receptors on the non-neuronal cholinergic system (NNCS) With the continuous deepening of the research on muscarinic ACh receptors, a unique cholinergic regulatory factor production and circulatory system was discovered in recent years, which has attracted widespread attention from pharmacologists

Ann Oncol 33: 929938