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NAD+ supports fundamental energy pathways in all cells, including cancer cells, raising concern that artificially boosting NAD+ might fuel malignancy growth or interfere with certain cancer treatments

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Proc Natl Acad Sci 67:7478 Kong YK, Song K-S, Jung ME et al (2022) Discovery of GCC5694A: a potent and selective sodium glucose co-transporter 2 inhibitor for the treatment of type 2 diabetes