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[DOI] [PubMed] [Google Scholar] 264.Xu C, Xu J, Xiao L, Li Z, Xiao Y, Dargusch M, et al

Hydroxocobalamin in Neo-B12 Injection is the precursor for the enzyme co-enzyme B12 and this reacts with the enzyme Methylmalonyl Coenzyme A mutase, an isomerase required for the conversion of methylmalonate to succinate, an important step in production of lipoprotein in myelin sheath tissue, which could cause neurological problems

This routine advice on discharge and post-operative visits involves educating patients on the need for routine replacement with intramuscular injections of VB12 in all TG and discussing patient choice to have B12 levels monitored and replaced as required by the GP or replaced routinely by the GP