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Causality assessment tool One commonly used clinical assessment method for evaluating the likelihood that a drug is responsible for liver injury, based on clinical and laboratory, is the Roussel Uclaf Causality Assessment Method (RUCAM)

Comprehensive Physiology , 4 (1), p.177

however, restarting requires rebuilding tolerance and repeating the dosing escalation process

145 Therefore, maintaining gut microbial homeostasis and enhancing both anti-inflammatory and antioxidant capacity may represent promising strategies for delaying immune aging and promoting healthy longevity