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(January 2026)

Full report: 436 Comments Dchas Life Sciences 338 followers Pharmacists Simplify Pneumococcal Vaccine Guidance While Addressing Vaccine Fatigue in Adults: Alyssa Modic, PharmD, explains how pharmacists can clarify pneumococcal vaccine schedules, manage co-administration decisions, and reframe vaccination conversations for patients

Vitamin B12 deficiency is particularly important to consider, especially in patients also taking metformin, which is known to reduce B12 levels with long-term use (MHRA Drug Safety Update)

Other long-term considerations include gastrointestinal adaptation (most patients find side effects diminish significantly after the first 3-6 months), nutritional deficiencies that can develop with prolonged reduced caloric intake, and the psychological adjustment of maintaining a dramatically different body weight and relationship with food