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Several enzymatic and non-enzymatic defence mechanisms that guard cells against free radical damage have been identified in different cellular localizations, including mitochondria, plasma membrane, endoplasmic reticulum, peroxisomes, and cytosol

Petsouki, E., Cabrera, S

The highest concentration of glutathione is found in the liver where it offers antioxidant support for liver tissue protection and p450 phase II conjugation pathways a possible source of reactive oxygen species