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For a deeper look at how the two antioxidants work together, read our guide on taking vitamin C together with glutathione

The reduction of the NADP pool suggests that the electron influx into the NADP pool by metabolism more than compensates for the electron efflux to the anti-oxidant systems, and that glutathione reductase activity, catalysing the reduction of glutathione from NADPH, is limiting under the specific conditions of re-oxygenation after hypoxia

Science 295 , 321324 (2002)

Both substances can individually cause liver damage, and their combined effects can lead to severe consequences such as toxicity, gastrointestinal issues, impaired judgment and coordination, and masking of symptoms