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These notably include secondary metabolites and exogenous substrates often referred to as xenobiotics, usually for their detoxification, subsequent transport or export

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In the Swedish ABIS cohort, oxPTM-INS-Ab were present in 82% children progressing to clinical T1D compared to 19% in those who did not progress despite having one or more standard islet-autoantibodies after a median follow-up of 10.8 years (interquartile range 7.7-12.8)

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