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Palpitations are not commonly reported in clinical studies

The -subunit of hCG has a highly glycosylated 24-amino acid C-terminal tail absent from LH, which increases receptor activity and slows metabolic clearance resulting in a half-life of approximately 36 hours for hCG compared to just 30 minutes for LH, making hCG an extended-duration pharmacological analogue of LH for receptor biology research

References U.S

[2] Ongoing research comparing various long-acting estrogen esters suggests that estradiol cypionate provides a favorable pharmacodynamic window, but head-to-head trials remain limited and further study could clarify dosing equivalencies in diverse patient populations