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9.4 GSH-mediated immunotherapy Cancer immunotherapies, such as vaccines and immune checkpoint inhibitors, are most effective when their activity is confined to tumor sites

Pregnant or breastfeeding women, individuals with kidney or liver disorders, and those allergic to glutathione should avoid this treatment

Raw data Raw RNA sequencing data were demultiplexed and converted to FASTQ format using Illuminas Consensus Assessment of sequence and Variation (CASAVA) ( FASTQ files were aligned to the reference genome with STAR (two-pass mode) 56 , and TopHat 57 , and transcript quantification was performed using Cufflinks 58

GPX4 and TfR1 proteins were overexpressed in some TC cell lines compared to HThF cells