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Description

Tirzepatide is a synthetic peptide drug that mimics the effects of two key incretin hormones: GLP1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)

Burke, W

In addition to its critical role in energy metabolism, it acts as an extracellular signaling molecule that binds to and activates its specific G-protein-coupled receptor (GPR91), a receptor in HSCs whose role in hepatic fibrosis remains unclear