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Approximately 2200 glutathionylation targets have been identied in mam- malian cells (called the glutathionylome) and protein glutathionyl adduct formation is required for toxin elimination, locomotion, embryonic development, neural activity, immune cell activation, and many other functions [ 19 24 ]

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Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice

FIGURE 8 5 Conclusion AFT induces renal dysfunction via the stimulation of oxidative stress, LPO, and inflammatory response, which leads to decreased egg nutritional value and increased AFT accumulation in the egg