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Playing the DISC: turning on TRAIL death receptor-mediated apoptosis in cancer

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Because of stabilization of the benzylic radical and cation, aromatic compounds can undergo benzylic position fragmentation

Finally, tissue sections were mounted with Vectashield plus DAPI (4,6-diamidino-2-phenylindole) (Vector Labs) and imaged with an LSM 980 confocal microscope (Zeiss)